Cystic fibrosis and physiological responses to exercise

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Exercise hyperemia and vasoconstrictor responses in humans with cystic fibrosis.

ATP released from circulating erythrocytes is a potential signal regulating muscle blood flow during exercise (exercise hyperemia), and intravascular ATP appears to blunt sympathetic vasoconstriction during exercise. Erythrocytes from patients with cystic fibrosis (CF) do not release ATP. The goal of the present study was to determine whether increases in forearm blood flow during exercise are ...

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Exercise in Cystic Fibrosis

Godfrey, S., and Mearns, M. (1971). Archives of Disease in Childhood, 46, 144. Pulmonary function and the response to exercise in cystic fibrosis. Results of physiological studies at rest and during exercise in 41 patients with cystic fibrosis of the lungs are presented. The patients were evenly distributed by age between 5 and 21 years, and were grouped into 3 clinical grades corresponding to ...

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Cardiorespiratory and sensory responses to exercise in adults with mild cystic fibrosis.

The purpose of this study was to evaluate cardiorespiratory fitness and reasons for exercise curtailment in a contemporary adult cystic fibrosis (CF) cohort with mild lung disease. Adults with mild CF (n = 19, forced expiratory volume in 1 s = 95 ± 17% predicted) were age-, sex-, ethnicity-, and body mass index-matched to healthy controls (n = 19) and underwent a detailed cardiopulmonary cycle ...

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1 Cardiorespiratory and sensory responses to exercise in adults with mild cystic fibrosis

Cardiorespiratory and sensory responses to exercise in adults with mild cystic fibrosis 1 2 Bradley S. Quon, Sabrina S. Wilkie, Yannick Molgat-Seon, Michele R. Schaeffer, 3 Andrew H. Ramsook, Pearce G. Wilcox, Jordan A. Guenette 4 5 1 Division of Respiratory Medicine, Department of Medicine, University of British Columbia, 6 Vancouver, BC, Canada 7 2 Centre for Heart Lung Innovation, Providence...

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Exercise and Cystic Fibrosis (CF) 2.0.

In 1989 we knew that exercise, including regular prescribed physical activity, could be safely performed and described some of the physiological responses to exercise in patients with cystic fibrosis (CF). Also in 1989, the genetic defect causing cystic fibrosis (CF) was identified leading to improvements in treatment that greatly extended the life span for these patients. Increased understandi...

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ژورنال

عنوان ژورنال: Expert Review of Respiratory Medicine

سال: 2014

ISSN: 1747-6348,1747-6356

DOI: 10.1586/17476348.2014.966693